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MiRNA-mediated regulation of Bmp2 during pathological calcification

ABSTRACT: Renal disease is a major risk factor for cardiovascular disease. BMP2 and its downstream effectors are strong implicators of pathological calcificatoin. We profiled miRNAs from Klotho mutant mice and from health mice to determine any potential biomarkers for predicting the progression of pathological calcification through targeting of BMP2 and its downstream effectors.

ORGANISM(S): synthetic construct Mus musculus

PROVIDER: GSE135759 | GEO | 2020/10/27

REPOSITORIES: GEO

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