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The effect of attenuated Salmonella typhimurium on the tumor epithelium in mouse colorectal cancer model

ABSTRACT: Bacterial cancer therapy (BCT) shows great promise for treatment of solid tumors, yet basic mechanisms of bacterial-induced tumor suppression remain undefined. We aimed to better understand the tumor epithelium-targeted mechanisms of BCT by using mouse models of intestinal tumorigenesis to assess the effectiveness and mechanisms of treatment with aromatase A-deficient Salmonella typhimurium (STm) delivered by oral gavage.

ORGANISM(S): Mus musculus

PROVIDER: GSE136029 | GEO | 2019/08/20

REPOSITORIES: GEO

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