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Expression data from primary murine CD8+ T cells incubated in AML cell or dendritic cell conditioned medium

ABSTRACT: During activation T cells need to undergo metabolic reprogramming for proper effector function. Disturbances in metabolic pathways lead to impaired T cell function. Active metabolic evasion of cancer cells lead to less immunosurveillance and uncontrolled tumor growth. We used microarrays to investigate the expression changes in T cells challenged with AML supernatants shedding light on the underlying mechanisms of metabolic evasion in leukemia.

ORGANISM(S): Mus musculus

PROVIDER: GSE136132 | GEO | 2023/08/21

REPOSITORIES: GEO

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