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Global effect of JTV or JTV-Alt overexpression in HeLa cells

ABSTRACT: JTV is not only a structural component of multi-aminoacyl-tRNA synthetase complex, but also a regulator of FBP that in turn controls c-Myc expression. In order to identify JTV target genes other than FBP and c-Myc, JTV or JTV-Alt (alternatively spliced form of JTV, enriched in the nucleus) protein was over-expressed in HeLa cells and global gene expression changes were monitored using cDNA expression microarray.

ORGANISM(S): Homo sapiens

PROVIDER: GSE13646 | GEO | 2011/05/18

SECONDARY ACCESSION(S): PRJNA110197

REPOSITORIES: GEO

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