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RNAseq analysis of CC strains after influenza A virus infection identifies genetic control of the host response

ABSTRACT: Gene expression changes in the lung was studied by RNAseq in different CC mouse strains infected with influenza A virus. Results: Strong differences between the genetically CC mouse strains can be observed in the activation of host defense genes. These differences can be related to genetic variants in the genome of the CC strains. Furthermore, different strains exhibit variant susceptibility to infections (body weight loss and survival). These differences can be correlated to differences in gene expression profiles.

ORGANISM(S): Mus musculus

PROVIDER: GSE136748 | GEO | 2020/07/08

REPOSITORIES: GEO

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