Transcriptomics

Dataset Information

0

Transcriptome Analysis of Candida albicans Biofilms Grown in the Presence of Arachidonic Acid and Fluconazole


ABSTRACT: Candida albicans is a commensal yeast within the human microbiota with significant medical importance because of its pathogenic potential. The yeast produces biofilms, which are highly resistant to available antifungals. High level of antifungal resistance by C. albicans biofilms has resulted in the need for alternative treatment. Polyunsaturated fatty acids such as arachidonic acid has been reported to increase the susceptibility of C. albicans biofilms to azole. However, the underlining mechanism is unknown. To unravel the mechanism behind this phenomenon, identification of differentially regulated genes in C. albicans biofilms grown in the presence of arachidonic acid, fluconazole, and the combination of both compounds was conducted using RNAseq.

ORGANISM(S): Candida albicans

PROVIDER: GSE137423 | GEO | 2020/08/25

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2012-03-14 | E-GEOD-36436 | biostudies-arrayexpress
2014-05-24 | GSE57930 | GEO
2008-11-05 | GSE11320 | GEO
2014-05-24 | E-GEOD-57930 | biostudies-arrayexpress
| PRJNA565419 | ENA
2008-11-04 | E-GEOD-11320 | biostudies-arrayexpress
2012-03-14 | GSE36436 | GEO
2021-01-31 | GSE136726 | GEO
2021-01-31 | GSE159545 | GEO
2020-10-06 | GSE148341 | GEO