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Dietary enrichment of BCAA ameliorates cardiac metabolism and function in failing heart

ABSTRACT: Here we show that a specific diet in which dietary protein content has been replaced with a defined-amino acid formula enriched with BCAA, has a remarkable effect in treating heart failure (HF). In particular, we demonstrate that our dietary intervention has a theraputic relevance in the setting of preestablished disease, providing a critical rationale for further development of dietary interventions for HF.

ORGANISM(S): Mus musculus

PROVIDER: GSE137669 | GEO | 2021/09/01

REPOSITORIES: GEO

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Dietary enrichment of BCAA ameliorates cardiac metabolism and function in failing heart

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