Gene expression analysis from placenta of Cornelia de Lange Syndrome (CdLS) mouse models
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ABSTRACT: CdLS is caused by mutaion in cohesin and associated proteins, such as Nipbl and Hdac8. We performed RNA seq analysis from Nipbl+/- and Hdac8-/0 placenta with their respective wild type control at 14.5 dpc, to identify molecular pathways affected. To understand the effect of protein kinase R (PKR) on gene expression we also performed RNA seq analysis from Nipbl+/- and Hdac8-/0 placenta lacking PKR.
ORGANISM(S): Mus musculus
PROVIDER: GSE138687 | GEO | 2020/07/27
REPOSITORIES: GEO
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