Transcriptomics

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Gene expression analysis from placenta of Cornelia de Lange Syndrome (CdLS) mouse models


ABSTRACT: CdLS is caused by mutaion in cohesin and associated proteins, such as Nipbl and Hdac8. We performed RNA seq analysis from Nipbl+/- and Hdac8-/0 placenta with their respective wild type control at 14.5 dpc, to identify molecular pathways affected. To understand the effect of protein kinase R (PKR) on gene expression we also performed RNA seq analysis from Nipbl+/- and Hdac8-/0 placenta lacking PKR.

ORGANISM(S): Mus musculus

PROVIDER: GSE138687 | GEO | 2020/07/27

REPOSITORIES: GEO

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