MicroRNA Expression Profiles Analysis in Mouse Pancreatitis Tissue With or Without Hypertriglyceridemia

ABSTRACT: The crucial roles of miRNAs have been implicated in various pathological processes, including pancreatitis. However, roles of miRNAs in hypertriglyceridemia-associated pancreatitis have not been reported. Pancreatitis tissue from mice with or without hypertriglyceridemia were analyzed for microRNA profiling. Using qPCR verification, we further identified miR-153 as the most upregulated miRNA in mice with hypertriglyceridemia. This work provide potential therapeutic targets for the treatment of hypertriglyceridemia-associated pancreatitis.

ORGANISM(S): Mus musculus

PROVIDER: GSE138745 | GEO | 2022/10/01

REPOSITORIES: GEO