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High throughput CRISPR screening identifies genes involved in macrophage viability and inflammatory pathways I

ABSTRACT: Whole-genome pooled sgRNA screen using immortalize bone marrow-derived mouse macrophages with Cas9 and an NFKB-GFP reporter system (iBMDM-NFKB-Cas9) The goal of this experiment was to 1) identify regulators of NFKB signaling 2) identify genes important for viability

ORGANISM(S): Mus musculus synthetic construct

PROVIDER: GSE138786 | GEO | 2021/03/02

REPOSITORIES: GEO

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High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways.

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