Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome response of Pseudomonas aeruginosa PA14 to antimicrobial peptides

ABSTRACT: We analyzed the transcriptome of P. aeruginosa grown for 16h in the presence or absence of 0.25 x MIC of polymyxinB, G3KL or T7

ORGANISM(S): Pseudomonas aeruginosa PA14

PROVIDER: GSE139257 | GEO | 2019/10/23

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Pseudomonas aeruginosa PA14

Project description:Pseudomonas aeruginosa RNA-seq and Tn-seq in sub-MIC antimicrobials

| PRJNA291292 | ENA

Transcriptome response of Pseudomonas aeruginosa PA14 to antimicrobial peptides

Project description:Transcriptome response of Pseudomonas aeruginosa PA14 to antimicrobial peptides

| PRJNA578924 | ENA

Pseudomonas aeruginosa PA14 exposed to the aminothiol cysteamine during growth in synthetic cystic fibrosis sputum media (SCFM2)

Project description:Derived from coenzyme A degradation in mammalian cells, the aminothiol cysteamine may represent a promising new adjunct treatment for pulmonary exacerbations in cystic fibrosis (CF). This experiment aims to characterise the effect of sub-MIC cysteamine on P. aeruginosa strain PA14. Samples were cultured in SCFM2 (triplicate), and exposed to either cysteamine or a H2O control.

2021-11-01 | E-MTAB-10326 | biostudies-arrayexpress

Pseudomonas aeruginosa PA14, pqsE and PQS

2009-07-17 | GSE17116 | GEO

Pseudomonas aeruginosa PA14, mvfR and anthranilic acid analogs

Project description:The Pseudomonas aeruginosa MvfR-dependent QS regulatory pathway controls the expression of key virulence genes; and is activated via the extracellular signals 4-hydroxy-2-heptylquinoline (HHQ) and 3,4-dihydroxy-2-heptylquinoline (PQS), whose syntheses depend on anthranilic acid (AA), the primary precursor of 4-hydroxy-2-alkylquinolines (HAQs). We identified halogenated AA analogs that specifically inhibited HAQ biosynthesis and disrupted MvfR-dependent gene expression. These compounds restricted P. aeruginosa systemic dissemination and mortality in mice, without perturbing bacterial viability, and inhibited osmoprotection, a widespread bacterial function.

2009-07-17 | GSE17111 | GEO

Pseudomonas aeruginosa PAO1 virulent genes in the poplar rhizosphere

Project description:Pseudomonas aeruginosa PAO1 contacted with and without poplar roots gene expression Poplar contacted with and without PAO1 gene expression. All samples cultured in 1 x hrp + 0.25 % sucrose Keywords: Contact with different species

2007-03-18 | GSE5887 | GEO

Genomic DNA hybridization of Pseudomonas aeruginosa strains PAO1 and PA14

Project description:Genomic DNA from Pseudomonas aeruginosa strains PAO1 and PA14

2015-11-15 | GSE67038 | GEO

Expression profile for higA mutant of Pseudomonas aeruginosa PA14

Project description:The previously uncharacterized proteins HigB (unannotated) and HigA (PA4674) of Pseudomonas aeruginosa PA14 were found to form a type II TA system in which antitoxin HigA masks the RNase activity of toxin HigB through direct binding. To determine the physiological role of HigB/HigA in P. aeruginosa, a whole-transcriptome experiment was performed for the higA antitoxin deletion mutant of the PA14 strain compared to the wild-type PA14 strain. The rationale was that for the strain that lacks the antitoxin, the effect of the toxin could be discerned due to enhanced activity of the toxin. Furthermore, toxin HigB reduces production of the virulence factors pyochelin, pyocyanin, swarming, and biofilm formation.

2016-11-04 | GSE74730 | GEO

Pseudomonas aeruginosa PA14 wild-type vs the tpbA (PA14_13660) mutant

Project description:Microarray analysis for the biofilm cells of Pseudomonas aeruginosa PA14 wild-type vs the tpbA (PA14_13660) mutant in LB medium at 4 and 7 h at 37C

2009-05-23 | GSE13871 | GEO

Toxicogenomic analysis of sodium sodium hypochlorite antimicrobial mechanisms in Pseudomonas aeruginosa

Project description:In the present study, we employed Affymetrix Pseudomonas aeruginosa GeneChip arrays to investigate global gene expression profiles during the cellular response of Pseudomonas aeruginosa to sodium hypochlorite Keywords: Antimicrobial response

2007-12-04 | GSE7402 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data