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Alpha Ketoglutarate Prevents Age-related Osteoporosis via Regulating Histone Methylations

ABSTRACT: The aim of this study is to investigate the effect of aKG treatment on the self-renewal and lineage specification of mouse bone marrow derived mesenchymal stem/stromal cells (mBMSCs). The sequence reads were mapped to mouse genome (build mm10) using TopHat followed by Cufflinks. Expression of key genes was validated by SYBR Green RT-qPCR assays.

ORGANISM(S): Mus musculus

PROVIDER: GSE139496 | GEO | 2020/09/08

REPOSITORIES: GEO

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Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations.

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