Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome anaylisis of WT and GFAT-1 G451E engineered N2a cells by RNA-Seq

ABSTRACT: Transcriptome of N2a cells carrying a GFAT-1 gain-of-function point mutation that results in a G451E amino acid substitution were compared to WT N2a transcriptome profiles. Three replicates of both cell lines were analyzed. Additionally WT N2a cells were treated with 10 mM GlcNAc for 24h prior to transcriptome analysis resulting in a third dataset with 3 replicates.

ORGANISM(S): Mus musculus

PROVIDER: GSE140357 | GEO | 2019/11/14

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

miRNA sequencing of exosomes derived from N2A and APP-N2A cells

Project description:APP misexpression plays a crucial role in triggering a complex pathological cascade, leading to Alzheimer’s disease (AD). The aim of this study is for determine the influence of APP ectopic expression on the miRNA profiles of neuronal exosomes. In study, miRNA sequencing was done using the exosomes derived from N2A (control) and APP-N2A (N2A with APP overexpression).

2022-03-30 | E-MTAB-11106 | biostudies-arrayexpress

Transcriptome anaylisis of WT and GFAT-1 G451E engineered N2a cells by RNA-Seq

Project description:Transcriptome anaylisis of WT and GFAT-1 G451E engineered N2a cells by RNA-Seq

| PRJNA589330 | ENA

Comparing gene expression in untransfected and transfected mouse neuronal (N2A) cell line

Project description:We compared the gene expression in untransfected N2A cells and in pCDNA3.1myc/his vector transfected N2A cells 1 sample each of untransfected and transfected N2A cells were analyzed

2012-02-29 | E-GEOD-36142 | biostudies-arrayexpress

miRNA sequencing of exosomes derived from N2A and APP-N2A cells

Project description:miRNA sequencing of exosomes derived from N2A and APP-N2A cells

| PRJEB48466 | ENA

mRNA sequencing of circCpsf6 silencing models in N2A cells

Project description:mRNA sequencing was performed to explore involved mRNAs when circCpsf6 was silenced in N2A cells.The differential expression of mRNAs caused by the knockdown of circCpsf6 was revealed in the volcano plot.Heatmaps indicated the upregulated and downregulated clusters of differential mRNAs when circCpsf6 was silenced in N2A cells

2021-08-01 | GSE164028 | GEO

RNA-seq using mouse Neuro-2A (N2A) neuroblastoma cells

Project description:To identify high-confidence NMD targets in mouse N2A neuroblastoma cells, we used our established transcriptome-wide RNA sequencing (RNA-seq) methodologies. Through parallel analyses of RNA-seq upon UPF1-knockdown (KD) and RNA immunoprecipitation (RIP-seq) footprinting of p-UPF1-bound RNAs, we identified 1027 high-confidence neuronal NMD targets.

2021-10-25 | GSE180136 | GEO

Exon array analysis of N2A cells after knocking down FUS

Project description:To analyze the role of Fus, Ewsr1, and Taf15 in alternative RNA processing, we performed exon array analysis in N2A cells using exon arrays. N2A cells were transfected with siRNA using Lipofectamine RNAiMAX (Life Technologies) according to the manufacturer’s instructions.

2020-08-10 | GSE60694 | GEO

miRNA sequencing of circCpsf6 silencing models in N2A cells

Project description:To search and identify the potential downstream miRNAs of circCpsf6, miRNA sequencing analysis was performed on circCpsf6 silencing models in N2A cells. The differential expression of miRNAs caused by the knockdown of circCpsf6 was revealed in the volcano plot.Heatmaps indicated the upregulated and downregulated clusters of differential miRNAs in N2A cells when circCpsf6 was silenced.

2021-08-01 | GSE164029 | GEO

Gene expression and alternative splicing profiles of N2a siEwsr1 cells

Project description:N2a cells treated with either control or siEwsr1 oligonucleotides

2022-04-13 | GSE173439 | GEO

Mus musculus strain:N2a

Project description:Mus musculus strain:N2a Raw sequence reads

| PRJNA629900 | ENA