Transcriptomics

Dataset Information

0

A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord


ABSTRACT: The Drosophila ventral nerve cord (VNC) receives and processes descending signals from the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory information from the periphery and sends ascending signals to the brain. We used single-cell transcriptomics to generate an unbiased classification of cellular diversity in the VNC of five-day old adult flies. We produced an atlas of 26,000 high-quality cells, representing more than 100 transcriptionally distinct cell types. The predominant gene signatures defining neuronal cell types reflect shared developmental histories based on the neuroblast from which cells were derived, as well as their birth order. Cells could also be assigned to specific neuromeres using adult Hox gene expression. This single-cell transcriptional atlas of the adult fly VNC will be a valuable resource for future studies of neurodevelopment and behavior.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE141807 | GEO | 2020/04/16

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-02-14 | GSE235231 | GEO
2016-03-05 | GSE78889 | GEO
2023-09-30 | GSE241968 | GEO
2021-01-30 | GSE165824 | GEO
2021-07-26 | GSE179285 | GEO
2019-11-26 | GSE140914 | GEO
2021-02-16 | GSE155610 | GEO
2015-04-10 | E-GEOD-67707 | biostudies-arrayexpress
2022-02-21 | GSE185224 | GEO
2022-05-16 | E-MTAB-11452 | biostudies-arrayexpress