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Transcriptomic, epigenetic and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus [scRNA-seq]

ABSTRACT: Two subpopulations of low density granulocytes (LGDs) were defined in terms of different gene expression patterns, transcriptional and epigenetic features as well as functions. This study provides insights into the mechanism of immune dysregulation and the vascular damage characteristic of lupus.

ORGANISM(S): Homo sapiens

PROVIDER: GSE142016 | GEO | 2019/12/13

REPOSITORIES: GEO

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