Effect of Ythdf2 in haematopoiesis [meRIP-seq]
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ABSTRACT: The mRNA m6A reader YTHDF2 is overexpressed in human acute myeloid leukaemias. To understand the role of YTHDF2 in normal haematopoiesis and ageing, we performed SMART-seq on haematopoietic stem cells (HSCs) derived from young and aged (1 year old) mice. In parallel, to identify transcripts likely methylated in HSCs we performed meRIP-seq analysis of c-Kit+ cells.
ORGANISM(S): Mus musculus
PROVIDER: GSE142020 | GEO | 2020/10/29
REPOSITORIES: GEO
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