Multiplexed single-cell autism modeling reveals convergent mechanisms altering neuronal differentiation
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ABSTRACT: We coupled dCas9-based transcriptional repression of autism and neurodevelopmental disease genes to single-cell RNA-sequencing in the context of human neuron differentiation to identify the unique and shared consequences of these perturbations in a pooled experimental format.
ORGANISM(S): Homo sapiens
PROVIDER: GSE142078 | GEO | 2020/06/20
REPOSITORIES: GEO
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