Transcriptional responses of colon tissues following ex-vivo colonization with human microbiome

ABSTRACT: Purpose: The goal of this study is to compare colonic transcriptional responses following ex-vivo colonization with fecal samples collected from multiple sclerosis patients, before and after Propionic acid treatment and between the patients that responded or not to the therapy. Methods: Bulk whole-tissue mRNA profiles of 13-day-old wild-type mice colons were generated by deep sequencing, in triplicate, using Illumina NextSeq platform.

ORGANISM(S): Mus musculus

PROVIDER: GSE142748 | GEO | 2020/09/29

REPOSITORIES: GEO