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Viral integration transforms chromatin to drive oncogenesis

ABSTRACT: We report that the integration of the human papillomavirus into the host genome increases chromatin accessibility, transcription, and CTCF binding within 100 kbp of the integration site which promotes oncogenesis in some patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE143026 | GEO | 2020/02/14

REPOSITORIES: GEO

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