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Exploitable, highly context-specific astrocytes

ABSTRACT: To investigate the functional heterogeneity of astrocytes from a defined brain region, we designed 12 experimental manipulations including Huntington's disease models, pathological challenges, ionic and GPCR signaling alterations, and analyzed the transcriptomic profiles of striatal astrocytes. From the analyses, we have identified context-specific changes of striatal astrocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE143475 | GEO | 2020/11/17

REPOSITORIES: GEO

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Exploitable, highly context-specific astrocytes

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