Transcriptomics

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Myeloid cell analysis during a pro-fibrotic ischemia-reperfusion and cardiotoxin muscle injury.


ABSTRACT: Myeloid cells are critical to the development of fibrosis following muscle injury, however, the mechanism of their role in fibrosis formation remains unclear. Here we demonstrate that myeloid cell-derived TGF-β1 signaling is increased in a pro-fibrotic ischemia-reperfusion and cardiotoxin (IR/CTX) muscle injury model. This study analyzes scRNAsequencing from the fibrotic region after a pro-fibrotic ischemia-reperfusion and cardiotoxin muscle injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE144270 | GEO | 2020/01/28

REPOSITORIES: GEO

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