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RNA-Seq of 3 breast cancer models to investigate NFIB signalling role in metastatic colonization.

ABSTRACT: Next Generation Sequencing was applied to investigate molecular mechanisms underlying the increased metastatic colonization driven by Nfib. Global transcriptional profiling of primary tumours derived from Nfib high-expression models (LM1 and LM9) and Nfib low-expression models (HR1) allowed to identify Ero1l as a mediator of metastasis upon Nfib upregulation.

ORGANISM(S): Mus musculus

PROVIDER: GSE144392 | GEO | 2021/01/15

REPOSITORIES: GEO

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