Transcriptomics

Dataset Information

0

Whole transcriptome analysis of mouse aortas and kidneys with or without deletion of the EGFR in vascular smooth muscle cells after 18 weeks of high fat diet


ABSTRACT: Obesity causes diabetes type 2 (DMT2) leading to vascular dysfunction and finally renal end-organ damage. Vascular smooth muscle (VSM) EGF receptor (EGFR) modulates vascular wall homeostasis in part via serum response factor (SRF), a major regulator of VSM differentiation and a sensor for glucose. We investigated the role of VSM-EGFR during obesity-induced renovascular dysfunction and the EGFR-hyperglycemia crosstalk.

ORGANISM(S): Mus musculus

PROVIDER: GSE144838 | GEO | 2020/03/01

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2021-04-01 | GSE158197 | GEO
2021-12-01 | GSE163551 | GEO
2022-01-10 | GSE162769 | GEO
2022-01-10 | GSE162768 | GEO
| PRJNA605107 | ENA
2023-05-26 | E-MTAB-12855 | biostudies-arrayexpress
2021-01-18 | GSE160585 | GEO
| PRJNA664331 | ENA
2018-03-09 | GSE64310 | GEO
2019-12-20 | GSE64307 | GEO