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Impact of high salinity and the compatible solute glycine betaine on global gene expression of Bacillus subtilis

ABSTRACT: In order to reveal so far unknown facets of the adaptation of B. subtilis to growth under high-salinity conditions, a whole-transcriptome analysis of B. subtilis BSB (168 Trp+) was performed using strand-specific tiling arrays (tiling step of 22 nucleotides). In addition, the effects of glycine betaine (GB) were analyzed under high salinity and standard growth conditions in a chemically defined medium. Important novel findings were a sustained low-level induction of the SigB-dependent general stress response and strong repression of biofilm matrix genes under high-salinity conditions. GB influences gene expression not only under high-salinity, but also under standard growth conditions without additional salt.

ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 Bacillus subtilis

PROVIDER: GSE145124 | GEO | 2020/05/18

REPOSITORIES: GEO

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Gene regulation in Bacillus subtilis by the compatible solute glycine betaine

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