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Effect of LSD1 knockdown on histone H3K4 methylation in HEL human erythroleukemia cell line.

ABSTRACT: To understand the role of LSD1 in regulating histone H3K4 methylation status, ChIP-seq analyse of mono- and di-methylated H3K4 in LSD1-KD HEL cells were performed. The analyses revealed demethylation of H3K4me1 and H3K4me2 by LSD1 at regulatory regions including CEBPA gene enhancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE145399 | GEO | 2021/05/04

REPOSITORIES: GEO

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