Expression data from INS1E cells stimulated with vitamin D metabolites and glucose

ABSTRACT: Studies have shown that vitamin D can enhance glucose-stimulated insulin secretion (GSIS) and change the expression of genes in pancreatic β-cells. Still the mechanisms linking vitamin D and GSIS are unknown. We used an established β-cell line, INS1E. INS1E cells were pre-treated with 10 nM 1,25(OH)2vitamin D or 10 nM 25(OH)vitamin D for 72 hours and stimulated with 22 mM glucose for 60 minutes. RNA was extracted for gene expression analysis.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE145460 | GEO | 2020/02/19

REPOSITORIES: GEO