Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Functional subnetwork modules and discovery of hub genes with signal peptide using RNA-Seq (hybrid 33k44 vs. inbred B73)

ABSTRACT: We performed a systematic computational network-based analysis of large-scale F. verticillioides RNA-seq datasets to identify gene subnetwork modules associated with virulence and fumonisin regulation.

ORGANISM(S): Fusarium verticillioides

PROVIDER: GSE146208 | GEO | 2020/03/03

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Functional subnetwork modules and discovery of hub genes with signal peptide using RNA-Seq (hybrid 33k44 vs. inbred B73)

Project description:Functional subnetwork modules and discovery of hub genes with signal peptide using RNA-Seq (hybrid 33k44 vs. inbred B73)

| PRJNA609706 | ENA

Functional subnetwork modules and hub gene discovery using RNA-Seq (wild type Fusarium verticillioides and the FSR1 mutant)

Project description:Using RNA-Seq datasets, we identified subnetwork modules (group of genes) and key functional (hub) genes associated with the fungal pathogenicity by developing a computational pipeline with network-based comparative analusis approach

2017-12-21 | GSE108365 | GEO

Functional subnetwork modules and hub gene discovery using RNA-Seq (wild type Fusarium verticillioides and the FSR1 mutant)

Project description:Functional subnetwork modules and hub gene discovery using RNA-Seq (wild type Fusarium verticillioides and the FSR1 mutant)

| PRJNA423270 | ENA

Expression analysis of wild type Fusarium verticillioides cultured in liquid media

2009-12-31 | GSE16900 | GEO

Expression analysis of Fusarium verticillioides wild-type cultured in liquid media

2012-05-21 | GSE34168 | GEO

Expression analysis of Fusarium verticillioides wild-type cultured in liquid media

Project description:Investigation of whole genome gene expression level changes over time of Fusarium verticillioides wild-type in liquid fumonisin inducing media (GYAM) Fusarium verticillioides produces a polyketide derived mycotoxin, fumonsin, over time in liquid media, Proctor et al, Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis, Fungal Genetics and Biology, 38:237-249 Wild type F. verticillioides strain 7600 cultured for two and five days in liquid GYAM.

2012-05-20 | E-GEOD-34168 | biostudies-arrayexpress

Fusarium verticillioides wild type versus LAE1 deletion mutant at 6 days on fumonisin inducing medium

Project description:Investigation of whole genome gene expression level changes after 6 days growth of Fusarium verticillioides wild-type and LAE1 deletion mutant in liquid fumonisin inducing media (GYAM) Fusarium verticillioides produces a polyketide derived mycotoxin, fumonsin, over time in liquid media, Proctor et al, Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis, Fungal Genetics and Biology, 38:237-249.

2012-12-01 | GSE32608 | GEO

Expression analysis of wild type Fusarium verticillioides cultured in liquid media

Project description:Investigation of whole genome gene expression level changes over time of Fusarium verticillioides wild-type in liquid fumonisin inducing media (GYAM). Fusarium verticillioides produces a polyketide derived mycotoxin, fumonsin, over time in liquid media (Proctor et al, Co-expression of 15 contiguous genes delineates a fumonisin biosynthetic gene cluster in Gibberella moniliformis, Fungal Genetics and Biology, 38:237-249). A twelve chip study using total RNA recovered from twelve wild type cultures of Fusarium verticillioides. Each chip measures the expression level of 13,288 genes with thirteen 60-mer probe pairs per gene.

2010-05-16 | E-GEOD-16900 | biostudies-arrayexpress

Fusarium verticillioides wild type versus LAE1 deletion mutant at 6 days on fumonisin inducing medium

2012-12-01 | E-GEOD-32608 | biostudies-arrayexpress

FVSTUA is a Key Regulator of Sporulation, Toxin Synthesis and Virulence in Fusarium verticillioides

Project description:Fusarium verticillioides is one of the most important pathogens of maize, causing rots and producing fumonisin mycotoxins during infection. Ingestion of fumonisin-contaminated corn causes underperformance and even fatal toxicity in livestock and is associated with neural tube birth defects, growth stunting in children and some cancers. StuA, an APSES class transcription factor, is commonly a major developmental transcriptional regulator in fungi. It has been shown to regulate crucial developmental processes, such as sporulation, virulence and mycotoxin synthesis among others. In this study, the role of FvSTUA in F. verticillioides was examined by characterizing ∆FvstuA deletion mutants functionally and transcriptomally. The deletion mutants exhibited slower vegetative growth, stunted aerial hyphae and significant reductions in microconidiation. Macroconidiation and hydrophobicity of the deletion strains were reduced as well. Additionally, fumonisin production by and virulence of the deletion mutants were greatly reduced. Transcriptomic analysis revealed downregulation of expression of several genes in the fumonisin and fusarin C biosynthetic clusters and differential expression of genes involved in conidiation and virulence. Nuclear localization of FvSTUA-tdTomato supported the likely function of FvSTUA as a transcription factor. Together, our results indicate that FvSTUA plays a global role in transcriptional regulation in F. verticillioides influencing morphogenesis, toxin production and virulence.

2020-11-01 | GSE144966 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data