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Emergent pro-metatastatic heterogeneity is shaped by clone interactions and restricted by VSIG1 VII

ABSTRACT: Our study prompeted us to assign, through spiked single cell RNAseq, metastatic function to transcriptomic cluster of colon cancer cells. Interactions between clones also uncover a restrictive anti metastatic influence that act intrinsically and non-cell automomously. We identify VSIG1 as critical mediator of this influence.

ORGANISM(S): Homo sapiens

PROVIDER: GSE146316 | GEO | 2020/11/09

REPOSITORIES: GEO

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