Transcriptomics

Dataset Information

0

RNA sequencing to identify UNC-49-regulated genes in C. elegans defense against pathogen infection


ABSTRACT: To gain molecular insights on how UNC-49 regulates C. elegans innate immunity, we used RNA sequencing to profile gene expression in unc-49(e407) animals relative to wild-type animals with or without P. aeruginosa(PA14) infection. We found that UNC-49 suppresses the expression of insulin pathway genes, and lack of UNC-49-mediated suppression in unc-49(e407) animals contributes to their improved survival against P. aeruginosa infection.

ORGANISM(S): Caenorhabditis elegans

PROVIDER: GSE146406 | GEO | 2023/10/23

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2023-06-26 | GSE195835 | GEO
2022-12-15 | GSE155868 | GEO
2020-09-30 | GSE158729 | GEO
| PRJNA610518 | ENA
2021-01-31 | GSE149862 | GEO
2019-01-01 | GSE98574 | GEO
2019-10-15 | GSE122544 | GEO
2022-10-31 | GSE201604 | GEO
2024-08-15 | GSE251677 | GEO
2023-08-31 | GSE205337 | GEO