Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from Canton-S and D18 adult flies

ABSTRACT: Even after decades of living in the same laboratory environment two Drosophila melanogaster strains originating from North America (Canton-S) and Central Russia (D18) demonstrate a few differentially expressed genes some of which may be important for local adaptation (e.g. genes responsible for insecticide resistance). Genes with different level of expression between Canton-S and D18 strains belong to important metabolic pathways, for instance energy metabolism, carbohydrate metabolic process, locomotion, body temperature rhythm regulation and tracheal network architecture. We used microarrays to make transcriptome profiling of two laboratory strains of different geographical origin after long-term laboratory maintenance

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE146725 | GEO | 2020/04/10

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression data from Canton-S and D18 adult flies

Project description:Expression data from Canton-S and D18 adult flies

| PRJNA611769 | ENA

Epigenetics of Yakutia and Central Russia regions

Project description:Lobachevsky University DNAm dataset. Whole blood DNA Methylation (EPIC) profiles from healthy samples from two regions: central Russia (131 samples) and Yakutia (114 samples) obtained in the Laboratory of System Medicine for Healthy Aging, Lobachevsky State University of Nizhny Novgorod, Russia Dataset contains DNAm data from 245 healthy control samples from two regions: central Russia (131) and Yakutia (114). The following characteristics are available for all samples: sex, age, region. Healthy participants in the central Russia region were recruited in 2019–2022. Yakutian participants we recruited in 2022. All measurements were performed at the Laboratory of System Medicine for Healthy Aging, Lobachevsky State University of Nizhny Novgorod, Russia.

2023-12-14 | GSE234461 | GEO

Proteomics studies confirm CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana

Project description:Insecticide resistance is a worldwide threat for vector control around the world, and Aedes aegypti , the main vector of several arboviruses, is a particular concern. To better understand the mechanisms of resistance, four isofemale strains originally from French Guiana were isolated and analysed using combined approaches. The activity of detoxification enzymes involved in insecticide resistance was assayed, and mutations located at positions 1016 and 1534 of the sodium voltage-gated channel gene, which have been associated with pyrethroid resistance in Aedes aegypti populations in Latin America, were monitored. Resistance to other insecticide families (organophosphates and carbamates) was evaluated. A large-scale proteomic analysis was performed to identify proteins involved in insecticide resistance. Our results revealed a metabolic resistance and resistance associated with a mutation of the sodium voltage-gated channel gene at position 1016. Metabolic resistance was mediated through an increase of esterase activity in most strains but also through the shifts in the abundance of several cytochrome P450 (CYP450s). Overall, resistance to deltamethrin was linked in the isofemale strains to resistance to other class of insecticides, suggesting that cross- and multiple resistance occur through selection of mechanisms of metabolic resistance. These results give some insights into resistance to deltamethrin and into multiple resistance phenomena in populations of Ae. aegypti

2020-12-09 | PXD020408 | Pride

Transcriptomic analysis of metabolic resistance in Aedes aegypti populations from Saudi Arabia

Project description:A microarray experimental design with dye balancing was adopted to compare the gene expression profiles of the following experimental groups; Field collected Makkah and Jeddah strains unexposed to any insecticide Fully insecticide susceptible New Orleans and Rockefeller laboratory strains. Laboratory Jeddah strain (F5) without exposure to insecticides Laboratory Jeddah strains selected for deltamethrin resistance (F5). For each comparison (field, lab selected or unselected vs susceptible), three biological replicates were used. The two susceptible strains, New Orleans and Rockefeller served as reference.

2023-01-30 | E-MTAB-10671 | biostudies-arrayexpress

A Whole Transcriptional Linkage Analysis of Gene Co-Regulation in Insecticide Resistant House Flies, Musca domestica

Project description:Illumina HiSeq 2000 RNASeq was conducted on the mRNA fraction of three adult female Musca domestica strains. Two strains were the insecticide susceptible strains CS and aabys, which has five distinct recessive morphological markers, one on each of the five autosomes in M. domestica. The third strain was ALHF, which is a highly insecticide resistant strain obtained in Alabama. The reference transcriptome was generated de novo using Trinity. The coding trimmed sequences from Augustus were then used as the mapping reference for the individual FASTQ files from each strain. trace reads were mapped using RSEM to generate FPKM estimates. Gene expression levels were compared to the ALHF strain using EdgeR to identify genes that were downregulated in both aabys and CS.

2014-01-02 | GSE39327 | GEO

A Whole Transcriptional Linkage Analysis of Gene Co-Regulation in Insecticide Resistant House Flies, Musca domestica

2014-01-02 | E-GEOD-39327 | biostudies-arrayexpress

Drosophila melanogaster strain:Canton S

Project description:Drosophila melanogaster strain:Canton S Genome sequencing

| PRJNA246754 | ENA

RNA-seq analysis of gene expression in adult head of Canton-S and Bully lines

Project description:Goal: Identify genes that are differentially expressed in hyper-aggressive Bully line. We used wildtype Canton-S flies as control. We also explored the effect of developmental temperature on gene expression.

2017-03-01 | GSE94293 | GEO

Drosophila melanogaster strain:Canton-S

Project description:Drosophila melanogaster strain:Canton-S Raw sequence reads

| PRJNA607084 | ENA

Drosophila melanogaster strain:Canton S

Project description:Drosophila melanogaster strain:Canton S Raw sequence reads

| PRJNA765491 | ENA