Genomics

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Chromosomal rearrangements juxtapose the TERT coding sequence to strong enhancer elements


ABSTRACT: Chromatin immunoprecipitation (ChIP) sequencing with an anti-acetyl-H3K27 antibody showed an enhancer region rearranged to the TERT gene, and ChIP sequencing with an anti-BRD4 antibody showed BRD4 protein binding to the enhancer in TERT-rarranged neuroblasstoma PDX CCI-NB07-RMT cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE147181 | GEO | 2021/03/01

REPOSITORIES: GEO

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