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The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

ABSTRACT: The bone marrow microenvironment of leukemia plays a key role in leukemia progression, but its molecular complexity in pre-B acute lymphoblastic leukemia (B-ALL), the most common cancer in children, remains poorly understood. Here we use single-cell RNA sequencing to characterise the bone marrow microenvironment during B-ALL progression.

ORGANISM(S): Mus musculus

PROVIDER: GSE148115 | GEO | 2020/07/27

REPOSITORIES: GEO

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