RNA sequencing of mice primary Hepatic Stellate Cells with Exosomes from pancreatic cancer cells
Ontology highlight
ABSTRACT: Pancreatic ductal adenocarcinoma (PDAC) shows a remarkable predilection for liver metastasis. Prooncogenic secretome delivering and trafficking via exosomes is crucial for pre-metastatic microenvironment formation and metastasis. This study aims to explore the underlying molecular mechanisms of how PDAC derived exosomes (Pex) modulate the microenvironments of future sites of metastasis.So we dicided using Hepatic Stellate Cells to see their transcriptomes changing after Pex addition.
ORGANISM(S): Mus musculus
PROVIDER: GSE148139 | GEO | 2021/04/30
REPOSITORIES: GEO
ACCESS DATA