Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single-cell gene expression of anti-viral WT and Bcl3-deficient effector T cells

ABSTRACT: Single-cell gene expression of effector CD8+ T cells WT or Bcl3-deficient was determined by sRNAseq after LCMV Armstrong infection

ORGANISM(S): Mus musculus

PROVIDER: GSE148660 | GEO | 2021/01/02

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Single-cell gene expression of anti-viral WT and Thpok-deficient effector and memory T cells

Project description:Single-cell gene expression of effector and memory CD4+ and CD8+ T cells from WT or Thppok-deficient animals was determined by sRNAseq after LCMV Armstrong infection

2019-01-08 | GSE121002 | GEO

Gene expression in WT and Thpok-deficient LCMV-specific effector T cells

Project description:Gene expression of effector CD4+ and CD8+ T cells determined by RNAseq 7 days after LCMV Armstrong infection

2019-08-15 | GSE130474 | GEO

Gene expression in WT and Thpok-deficient LCMV-specific effector T cells after retroviral transduction

Project description:Gene expression of transduced effector CD4+ T cells determined by RNAseq 7 days after LCMV Armstrong infection

2019-08-15 | GSE130475 | GEO

Single-cell gene expression of anti-viral WT and Bcl3-deficient effector T cells

Project description:Single-cell gene expression of anti-viral WT and Bcl3-deficient effector T cells

| PRJNA625300 | ENA

Population gene expression of anti-viral CD4 T cells in Bcl6 and Blimp1 deficient conditions

Project description:Population gene expression of effector CD4+ T cells WT, Bcl6-deficient , Blimp1-deficient or Bcl6 Blimp1-deficient was determined by RNAseq after LCMV Armstrong infection

2021-11-05 | GSE149597 | GEO

Single-cell chromatin accessibility of anti-viral CD4 T cells in Bcl6 and Blimp1 deficient conditions

Project description:Single-cell chromatin accessibility of effector CD4+ T cells WT or Bcl6 Blimp1-deficient was determined by scATACseq after LCMV Armstrong infection

2021-11-05 | GSE149913 | GEO

Single-cell gene expression of anti-viral CD4 T cells in Bcl6 and Blimp1 deficient conditions

Project description:Single-cell gene expression of effector CD4+ T cells WT, Bcl6-deficient , Blimp1-deficient or Bcl6 Blimp1-deficient was determined by scRNAseq after LCMV Armstrong infection

2021-11-05 | GSE149912 | GEO

Gene expression in WT and Thpok-deficient LCMV-specific memory T cells

Project description:Gene expression of memory CD4+ and CD8+ T cells determined by RNAseq 30 days after LCMV Armstrong infection

2019-01-08 | GSE116519 | GEO

CHD7 promotes anti-viral short-lived effector CD8+ T cells

Project description:CD8+ T cells differentiate into two subpopulations in response to acute viral infection: memory precursor effector cells (MPECs) and short-lived effector cells (SLECs). MPECs and SLECs are epigenetically distinct; however, the epigenetic regulators required for formation of these subpopulations are mostly unknown. Here we performed an in vivo CRISPR screen in murine naive CD8+ T cells to identify the epigenetic regulators required for MPEC and SLEC formation, using the acute lymphocytic choriomeningitis virus (LCMV) Armstrong infection model. We identified the ATP-dependent chromatin remodeler chromodomain-helicase-DNA-binding-protein-7 (CHD7) as a positive regulator of SLEC formation, as knockout (KO) of Chd7 reduced SLECs numerically. In contrast, KO of Chd7 increased the formation of central memory T cells following pathogen clearance yet attenuated memory cell expansion following a rechallenge. These findings establish CHD7 as a novel positive regulator of SLEC and negative regulator of central memory T cell formation.

2024-09-23 | GSE274735 | GEO

miR-17~92 Regulates Effector and Memory CD8 T cell Fates by Modulating Proliferation in Response to Infection

Project description:miRNA profiling of Db-GP33-41 specific murine CD8 T cells following infection with LCMV Armstrong Various in-vivo subsets of antigen-specific CD8 T cells were FACS sorted and analyzed for miRNA expression profiling. Samples were purified from either uninfected animals or after days 4.5, 9 and >60 post infection with LCMV Armstrong.

2013-04-16 | E-GEOD-46052 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data