Transcriptomics

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Expression data of LPS-stimulated macrophages from wild-type, MyD88-/- and TRIF-/- mice.


ABSTRACT: Lipopolysaccharide (LPS), a Toll-like receptor (TLR) 4 ligand, activates intracellular signaling via adaptors, MyD88 and TRIF, leading to the expression of various genes including proinflammatory cytokines. We used microarrays to examine influence of MyD88 or TRIF deficiency in LPS-inducible gene expression. Keywords: Time course after LPS (100 ng/ml) stimulation

ORGANISM(S): Mus musculus

PROVIDER: GSE14890 | GEO | 2009/02/19

SECONDARY ACCESSION(S): PRJNA111959

REPOSITORIES: GEO

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