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Histone modifications regulated by HDAC5 in PDAC cells

ABSTRACT: HDAC5 belongs to Class IIa histone deacetylases and forms corepressor complex with HDAC3. To understand the epignetic regulations by HDAC5, we performed ChIP-seq analysis of H3K4me3, H3K27ac and H3K9ac in PDAC cells overexpressing GFP or HDAC5, and in HDAC5 escaper cells with HDAC5 knockdown or scramble control.

ORGANISM(S): Mus musculus

PROVIDER: GSE149125 | GEO | 2020/04/27

REPOSITORIES: GEO

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