Transcriptomics

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The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice


ABSTRACT: Ablation of the gustatory G-protein, GNAT3, in damage and KRAS G12D induced pancreatic transformation enhanced CXCL1 and CXCL2 expression, altered the immunoregulatory gene expression of CXCR2 expressing myeloid-derived suppressor cells, and increased gMDSC presence to promote the progression of metastatic pancreatic ductal adenocarcinoma.

ORGANISM(S): Mus musculus

PROVIDER: GSE149165 | GEO | 2021/04/21

REPOSITORIES: GEO

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