Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis of Mycobacterium Smegmatis ΔF6 vs. Wild type

ABSTRACT: The study was conducted to understand the role of F6 small non-coding RNA in M.smegmatis. The results are a description of transcriptome changes in M. smegmaits strain with deletion of a gene of small RNA F6 relative to wild type strain.

ORGANISM(S): Mycolicibacterium smegmatis

PROVIDER: GSE149173 | GEO | 2021/05/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Mycobacterium smegmatis: CarD depletion (mgm1703) vs Control (mgm1701)

Project description:Transcriptional profiling of Mycobacterium smegmatis comparing the effects of wild type levels of CarD expression with CarD depletion. Transcriptional profile of the mgm1701 control strain was compared with that of mgm1703, a strain where CarD transcription is regulated by a Tet-On system. Both strains were grown in the absence of anhydrotetracline for 13 hours in nutrient rich broth to allow for depletion of CarD transcription in mgm1703.

2009-07-01 | GSE15437 | GEO

Identification of microproteins in Mycobacterium smegmatis by proteogenomics

Project description:We employed a proteogenomics workflow to identify microproteins encoded by small Open Reading Frames (ORFs) in the genome of Mycobacterium smegmatis strain mc²155.

2022-04-21 | PXD025604 | JPOST Repository

RNA deep sequencing data of the whole transcriptomes of the wild-type and aa3 mutant strains of Mycobacterium smegmatis MC2 155

Project description:Our comparative RNA sequencing analysis of the wild-type strain of M. smegmatis and its isogenic aa3 mutant strain lacking the aa3 cytochrome c oxidase of the respiratory electron transport chain revealed that expression of the SigF regulon is strongly induced in the aa3 mutant relative to the wild-type strain

2020-07-29 | GSE155251 | GEO

Mycobacterium smegmatis: CarD depletion (mgm1703) vs Control (mgm1701)

2010-05-16 | E-GEOD-15437 | biostudies-arrayexpress

RNA deep sequencing data of the whole transcriptomes of the wild-type, sigB and sigE mutant strains of Mycobacterium smegmatis MC2 155

Project description:To identify the SigB and SigE regulons in Mycobacterium smegmatis MC2 155, we constructed the sigB and sigE mutant strains and profiled the transcriptomes of the wild-type and mutant strains. Differentially expressed genes were identified pair-wisely by means of the DEGseq package in R language. 110 and 271 genes are differentially expressed in the sigB and sigE mutant strains relative to the wild-type strain, respectively.

2022-03-29 | GSE199475 | GEO

Mycobacterium smegmatis - Comparison of wild type SMR5 and glnR deletion strain MH1 under nitrogen starvation

Project description:In this approach, total transcript of the Mycobacterium smegmatis wild type SMR5 and a glnR deletion strain was compared under nitrogen starvation. Transcript levels of 6 genes were enhanced, 125 genes reduced in the mutant strain. This experiment confirmed GlnR as the global regulator of nitrogen metabolism in M. smegmatis. Two biological replicates were analyzed.

2011-07-01 | GSE30234 | GEO

Mycobacterium smegmatis: I-SceI homing endonuclease generated genomic DNA damage (site(+), mgm182) vs control (site(-), mgm181)

Project description:Transcriptional profiling of Mycobacterium smegmatis comparing a strain undergoing I-SceI generated DNA damage at a single genomic locus versus a control strain with no I-SceI recognition sequence in its genome (and thus not undergoing double strand DNA breaks Gene designations are from the original annotation, not the updated

2011-07-15 | GSE30633 | GEO

Gene expression profile of wild-type and isoniazid resistant strains of Mycobacterium smegmatis

Project description:Understanding emergence of drug resistance in pathogens systematically is a major challenge. To address this issue, lab-evolved strain resistant to first-line tuberculosis drug, isoniazid (INH), was analysed. Transcriptome analysis of different conditions revealed genes that are differentially regulated in wild-type (WT) and isoniazid resistant (2XR and 4XR) strains. Microarray analysis was performed for WT, sub-MIC, 2XR and 4XR strains of Mycobacterium smegmatis. Overall, the numbers of DEGs observed are 1529 in sub-MIC (596 - up, 933 - down), 1381 (899 – up, 482 – down) in 2XR and 716 in 4XR (267 – up, 449 – down) conditions. 52 of them are seen to be up-regulated across all drug concentrations as compared to WT while 185 are seen to be down-regulated in all. Transcriptome analysis revealed that there are variations in gene expression pattern in the resistant strains as compared to WT strain. This indicates that differential regulation of genes is, in some way, responsible for conferring the phenotype to the organism.

2014-12-13 | GSE64132 | GEO

Mycobacterium smegmatis - Comparison of wild type SMR5 and amtR deletion strain YL1 under nitrogen starvation

Project description:In this approach, total transcript of the Mycobacterium smegmatis wild type was compared to a amtR deletion strain under nitrogen starvation. With this experiment, putative target genes of AmtR, a regulator protein of nitrogen metabolism, were identified. Two biological replicates were analyzed.

2011-07-01 | GSE30231 | GEO

Mycobacterium smegmatis - Comparison of wild type SMR5 and amtR deletion strain YL1 under nitrogen surplus

Project description:In this approach, total transcript of the Mycobacterium smegmatis wild type was compared to a amtR deletion strain under nitrogen surplus. With this experiment, putative target genes of AmtR, a regulator protein of nitrogen metabolism, were identified. Two biological replicates were analyzed.

2011-07-01 | GSE30235 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data