Methylation profiling

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Genome-wide DNA methylation analysis of lung carcinoma II


ABSTRACT: Complements GSE56044 with 36 additional samples belonging to the large-cell carcinoma (LCC) and large-cell neuroendocrine (LCNEC) histologies. LCC classification is according to WHO 2004 guidelines. Genomic DNA from 36 lung cancer samples was treated with bisulfite and hybridized to Illumina methylation 450K arrays using standard protocols. Signal intensities were obtained from GenomeStudio (Illumina), converted to beta-values, filtered, and normalized to remove biases between Infinium I and II probes. Both raw intensity values, signal detection p-values and the final normalized data are included for each sample.

ORGANISM(S): Homo sapiens

PROVIDER: GSE149521 | GEO | 2020/07/27

REPOSITORIES: GEO

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