Single-cell RNA-seq profiles of murine sarcoma tumors with vehicle and digoxin treatments
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ABSTRACT: Digoxin, a cardiac glycoside widely used in humans, acts through disruption to central carbon metabolism via on target inhibition of the Na+/K+ ATPase. Acute Digoxin treatment remodels the tumor microenvironment, leading to cell-type specific transcriptional reprogramming of metabolic processes.
ORGANISM(S): Mus musculus
PROVIDER: GSE149751 | GEO | 2022/04/01
REPOSITORIES: GEO
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