Transcriptomics

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Single-cell RNA-seq profiles of murine sarcoma tumors with vehicle and digoxin treatments


ABSTRACT: Digoxin, a cardiac glycoside widely used in humans, acts through disruption to central carbon metabolism via on target inhibition of the Na+/K+ ATPase. Acute Digoxin treatment remodels the tumor microenvironment, leading to cell-type specific transcriptional reprogramming of metabolic processes.

ORGANISM(S): Mus musculus

PROVIDER: GSE149751 | GEO | 2022/04/01

REPOSITORIES: GEO

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