Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

HDAC inhibitor PCI-24781 inhibits metastasis in breast cancer

ABSTRACT: RNA-seq analysis was performed to identify key signaling responding to PCI-24781 in MDA-MB-231

ORGANISM(S): Homo sapiens

PROVIDER: GSE150038 | GEO | 2021/05/07

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RUNX2 inhibits metastasis of breast cancer

Project description:RNA-seq analysis was performed to identify key signaling responding to RUNX2 knockdown in MDA-MB-231

2022-11-02 | GSE190249 | GEO

HDAC inhibitor PCI-24781 inhibits metastasis in breast cancer

Project description:HDAC inhibitor PCI-24781 inhibits metastasis in breast cancer

| PRJNA630975 | ENA

PRMT6 promotes breast tumorigenesis

Project description:RNA-seq analysis was performed to identify key signaling responding to PRMT6 knockdown in MDA-MB-231

2023-05-24 | GSE210948 | GEO

Arsenic trioxide inhibits lung metastasis of breast cancer by suppression of TP53, TGFβ and TNFα signaling pathways

Project description:Metastasis is the main cause of mortality of breast cancer. To explore the mechanisms of arsenic trioxide (ATO) in inhibition of breast cancer metastasis, ATO regulated genes in breast cancer MDA-MB-231 and LM2-4175 cells were studied. After data analysis, ATO regulated genes were involved in TP53, TGFβ and TNFα signaling pathways. Furthermore, TGFβ and TNFα activated genes in breast cancer MDA-MB-231 cells were studied.

2023-04-16 | GSE184828 | GEO

Neuropilin-1 Knockout and Rescue Confirm its Role to Promote Metastasis in MDA-MB-231 Breast Cancer Cells

Project description:To investigate the function of Neuropilin-1 (NRP-1) in breast cancer MDA-MB-231 cells. CRISPR-Cas9 gene editing was used to knockout (KO) the NRP-1 gene in MDA-MB-231 human triple-negative breast cancer cells. Differentially expressed genes (DEGs) were determined in NRP-1 KO and parental MDA-MB-231 cells using whole transcriptome next-generation sequencing.

2023-04-11 | GSE229031 | GEO

Gene expression profile in breast cancer cells

Project description:We report the gene expression patterns in MDA-MB-231 (a line selected for low metastatic ability), MDA-MB-231-1833 (its bone-tropic metastatic derivative line), MDA-MB-231p27CK-DD (a phosphomimetic cell line), MDA-MB-231-1833shp27 (p27 knockdown cell line), MDA-MB-231-1833PF1502 (PI3K inhibitor treatment). It shows that the gene expression pattern are regulated in a p27 phosphorylation-dependent manner.

2019-03-19 | GSE112445 | GEO

Identification of LncRNA Expression Signatures for breast cancer brain metastasis (BCBM)

Project description:To identify BCBM-relevant lncRNAs, we assessed the expression profiles of lncRNAs in parental MDA-MB-231 (231-PAR) cells and isogenic brain metastatic cells (231-BRN), which were isolated from brain-seeking 231-PAR cells

2017-03-01 | GSE79540 | GEO

Identification of circRNA Expression Signatures for breast cancer metastasis

Project description:To identify breast cancer metastasis-relevant circRNAs, we assessed the expression profiles of circRNAs in parental MDA-MB-231 (231-PAR) cells, isogenic brain metastatic cells (231-BM6), lung metastatic cells (LM2) and bone metastatic cells (1833), which were isolated from brain, lung or bone-seeking 231-PAR cells

2019-03-01 | GSE111504 | GEO

S-adenosylmethionine (SAM) treatment attenuates breast cancer growth, invasion, metastasis

Project description:This study examines the therapeutic plausibility of using universal methyl group donor S-adenosylmethionine (SAM) to block breast cancer development, growth, and metastasis. cancer. Anti-tumor and anti-metastatic activity of SAM was evaluated through a series of studies in vitro using two different human breast cancer cell lines and in vivo using a MDA-MB-231 xenograft model of breast cancer. The data shown in this array is obtained from control and SAM-treated MDA-MB-231 cell lines.

2017-04-28 | GSE98275 | GEO

YWHAB over-expression inhibits migration and invasion of breast cancer MDA-MB-231 cells

Project description:To investigate the function of YWHAB gene, we established MDA-MB-231 cell line overexpressing YWHAB gene.

2022-11-26 | GSE218458 | GEO