The transcriptional profile of neutrophils in different organs during pancreatic cancer
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ABSTRACT: It was previously demonstrated that myeloid cells assume a distinct transcriptional profile when infiltrating the brain during chronic inflammation. We demonstrated that neutrophils infiltrate the brain during pancreatic cancer. To determine if the transcriptional profile of brain-infiltrating neutrophils is distinct from those infiltrating other organs, we compared the gene signatures of brain-infiltrating neutrophils, circulating neutrophils, liver-infiltrating neutrophils, and tumor-infiltrating neutrophils to that of circulating neutrophils from healthy mice.
ORGANISM(S): Mus musculus
PROVIDER: GSE150061 | GEO | 2020/05/08
REPOSITORIES: GEO
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