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MicroRNA array analysis of HTR-8/Svneo cells with BHLHE40 knockdown or not.

ABSTRACT: Preeclampsia (PE), which results from abnormal placentation, acts as a primary cause of maternal and neonatal morbidity and mortality. However, the cause of abnormal development of placenta remain poorly understood. BHLHE40, a transcript factor, is up-regulated in PE placenta compared to normal placenta probably due to the stimulation by low oxygen, but the implication of BHLHE40 in PE pathogenesis is not elucidated. Therefore, we conducted transcriptional profiling of genes in HTR-8/Svneo cells with BHLHE40 knockdown or not.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE150113 | GEO | 2023/04/23

REPOSITORIES: GEO

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