Transcriptomics

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To identify novel targets of a histone acetyltransferase Gcn5 in Pichia pastoris


ABSTRACT: The regulation of gene expression in Pichia pastoris has so far involved study of transcription factors. However, there are factors other than transcription factors affecting mRNA synthesis such as coactivators, enhancers, and chromatin modifiers. This study is a first ever report on epigenetic regulation in Pichia pastoris where, a histone acetyltransferase is reported to regulate transcription of genes involved in utilization of alternate carbon sources. We employed RNA Seq to identify new targets of Gcn5 in methanol medium.

ORGANISM(S): Komagataella pastoris

PROVIDER: GSE150467 | GEO | 2022/12/31

REPOSITORIES: GEO

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