Transcriptomics

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Circuit and molecular architecture of a ventral hippocampal network


ABSTRACT: The ventral hippocampus (vHPC) is a critical hub in networks that process emotional information. While recent studies have indicated that vHPC projection neurons are functionally dissociable, the basic principles of how the inputs and outputs of the vHPC are organized remain unclear. Here we used viral and sequencing approaches to define the logic of the extended vHPC circuit. Through molecular profiling of vHPC projection neurons, we show that vHPC neurons with distinct projection targets differ in their transcriptional signatures.

ORGANISM(S): Mus musculus

PROVIDER: GSE150869 | GEO | 2020/08/03

REPOSITORIES: GEO

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