Transcriptomics

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The small regulatory RNA Lpr10 regulates the expression of RpoS in Legionella pneumophila


ABSTRACT: Legionella pneumophila (Lp) is a waterborne bacterium able to infect human alveolar macrophages, causing a severe pneumonia known as Legionnaires’ disease. In water, Lp grows inside ciliates and ameoba. Lp is able to survive for several months in water, while searching for host cells. In Lp, the sigma factor RpoS is important for survival in water. Several small regulatory RNAs (sRNA) are known to regulate the expression of RpoS in other bacteria. A previous transcriptomic study showed that RpoS positively regulates the sRNA Lpr10 in Lp. Microarray analysis was performed to investigate the genes regulated by Lpr10.

ORGANISM(S): Legionella pneumophila subsp. pneumophila Legionella pneumophila subsp. pneumophila str. Philadelphia 1

PROVIDER: GSE151162 | GEO | 2020/05/27

REPOSITORIES: GEO

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