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Effects of endogenous GDF11 on the odontogenic differentiation of dental pulp stem cells

ABSTRACT: Knockdown of endogenous GDF11 downregulated the odontogenic differentiation of human dental pulp stem cells (hDPSCs). We performed RNA-seq analysis on hDPSCs transfected with GDF11 small interfering RNA (siRNA) and control siRNA after 7 days of odontogenic induction, in order to investigate the underlying mechanisms of endogenous GDF11 regulating odontogenic differentiation in hDPSC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE151435 | GEO | 2020/06/03

REPOSITORIES: GEO

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Effects of endogenous GDF11 on the odontogenic differentiation of dental pulp stem cells

Project description:Effects of endogenous GDF11 on the odontogenic differentiation of dental pulp stem cells

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Characterization of odontogenic differentiation from human dental pulp stem cells using TMT-based proteomic analysis

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