Transcriptomics

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The transcriptome of 2 pairs of monozygotic twins clinically discordant for IgA nephropathy


ABSTRACT: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis involves both genetic and environmental factors. DNA methylation, the most studied epigenetic modification, was shown to play a role in IgAN. In two pairs of IgAN-discordant monozygotic (MZ) twins, here we assessed genome-wide DNA methylation profiling and gene expression profiling in order to characterize DNA methylation changes in IgAN and their potential influences on gene expression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE151454 | GEO | 2021/05/15

REPOSITORIES: GEO

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