Transcriptomics

Dataset Information

0

Anatomical diversity of dermis in homeostasis and wound repair


ABSTRACT: Skin has distinct characteristics depending on the anatomical site; however, the cell and molecular differences, and their functional implications, have been little described. RNA-sequencing of healthy adult mouse skin from the abdomen, back, and face/cheek has revealed that dermis from different sites is distinct, and that this aligns with their diverse embryonic origins (abdominal dermis develops from lateral plate mesoderm, dorsal dermis from paraxial mesoderm, and cheek dermis from neural crest). The functional implications for wound repair are evident from the differences in extracellular matrix and cell migration observed in tissue and dermal fibroblasts from these sites, and the histological and transcriptional variations during a wound response.

ORGANISM(S): Mus musculus

PROVIDER: GSE151850 | GEO | 2020/11/06

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA637413 | ENA
2022-09-30 | GSE214427 | GEO
2024-02-10 | GSE252023 | GEO
2022-12-31 | GSE162904 | GEO
2016-02-05 | GSE72264 | GEO
2013-07-03 | E-GEOD-39743 | biostudies-arrayexpress
2016-02-05 | E-GEOD-72264 | biostudies-arrayexpress
2020-10-13 | GSE159345 | GEO
| 2617589 | ecrin-mdr-crc
2018-08-31 | GSE112671 | GEO