Mutations on a novel brain-specific isoform of PGC1α leads to extensive upregulation of neurotransmitter-related genes and sexually dimorphic motor deficits in mice
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ABSTRACT: We identified a new brain-specific isoform of PGC1 α that is the main isoform in neurons. Mutation of this gene leads to a sex dimorphic gene expression program in the female cerebellum and to alter motor coordination
ORGANISM(S): Mus musculus
PROVIDER: GSE152224 | GEO | 2021/06/01
REPOSITORIES: GEO
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