Mutations on a novel brain-specific isoform of PGC1α leads to extensive upregulation of neurotransmitter-related genes and sexually dimorphic motor deficits in mice

ABSTRACT: We identified a new brain-specific isoform of PGC1 α that is the main isoform in neurons. Mutation of this gene leads to a sex dimorphic gene expression program in the female cerebellum and to alter motor coordination

ORGANISM(S): Mus musculus

PROVIDER: GSE152224 | GEO | 2021/06/01

REPOSITORIES: GEO